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Wednesday, February 27, 2013

Genetics Research Paper

The topic that I chose to write my paper on is Polycystic Kidney Disease. This is a genetically transmitted affection of the kidneys which occurs in humans and or so animals. Polycystic Kidney Disease is the most common genetic, life-threatening disease; it affects of all timeyplace 12.5 million people worldwide, and roughly 500,000 in the United States. The disease is characterized by multiple fluid filled cysts appearing in two kidneys. Those cysts reduce the kidney function, which results in eventual kidney failure. There atomic number 18 two different strains of the disease; Autosomal dominant polycystic kidney disease and Autosomal recessive PKD.
Autosomal dominant PKD occurs when in that respect are mutations in either the PKD-1 (located on chromosome 16) or PKD-2(located on chromosome 4) gene. The function of these genes are to make proteins which help transmit chemical substance signals to the cells nucleus. They also help with kidney development, organization, and function. If one refer has autosomal dominant PKD, in that location is a fifty portion chance the child will possess the diseases gene. However, about five to ten per centum of ADPKD happens spontaneously, with neither arouse carrying the gene. Autosomal dominant PKD is a late-onset genetic disease, gist the affected person can go for multiple decades without ever aiming any symptoms.

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Autosomal recessive PKD occurs when there are mutations in the PKHD-1 gene, which is located on the short strengthen of chromosome 6. The function of this gene is the same as the previous touching genes; to make proteins to transmit chemical signals to the cells nucleus. If just one parent carries this gene, the child will not sterilise the disease, but may pass the gene onto their future offspring. If both parents carry the gene, then the child has a twenty-five percent chance of having the disease, which means the parents genotype would have to both be heterozygous. The symptoms of autosomal recessive PKD often begin to show before birth, nicknaming it infantile PKD. Children born with this...If you want to line up a full essay, order it on our website: Ordercustompaper.com



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